Berve et al paper cover

OptoDrum paper by Berve et al, on Neuroinflammation

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In their recent paper Sex- and region-biased depletion of microglia/macrophages attenuates CLN1 disease in mice Kristina Berve et al, from the Department of Neurology at the , show that neuroinflammation can be attenuated by treatment with proper pharmacological substances.

This has beneficial consequences from the cellular to the behavioral level. For example, Berve et al show with our OptoDrum that vision degenerates strongly in Ppt1–/– mice due to optic nerve atrophy. Pharmacological inhibition of innate immune cells ameliorates those effects.

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