At this year’s ARVO, one of our OptoDrum users – Ms Anna Potenski from Columbia University – is presenting a poster on the topic of “Elucidating endothelial caspase-9 signaling pathways in retinal vein occlusion” containing OptoDrum data.
OptoDrum Applications – Sodium Iodate Model of Retinal Degeneration
In this video of our series “OptoDrum Applications” Prof. Volker Enzmann from the University of Bern presents research with the Sodium Iodate Model (NaIO3) of Retinal Degeneration in mice.
Journal Club: Measuring Visual Acuity and Contrast Sensitivity by Optomotor Reflex in Rodents
In vision research, observing the optomotor reflex (OMR) is an important and widely established method for assessing visual acuity and contrast sensitivity in rodents. In this event, we will hear about several applications of OMR measuremnts, ranging from quantification of retinal degeneration to characterization of night vision.
Journal Club: Restoring vision – Optogenetic gene therapy targeted at human ON-bipolar cells
Optogenetic gene therapy holds great promise for healing blindness. Hulliger et al have developed a new promoter that effectively targets human ON bipolar cells. This is an important step towards clinical applications of optogenetic gene therapy for restoring vision.
Advent Calendar Raffle 2020: We Have a Winner for our DarkAdapt Box!
The lot has now fallen: We have a winner for our Advent calendar raffle from December 2020 where you could win one of our DarkAdapt boxes.
Journal Club: The role of Nogo-A in visual deficits induced by retinal injury.
Nogo-A, an inhibitor of neural growth, prevents regeneration after injury. Blocking of Nogo-A aides recovery, also in the visual system after retinal damage. Baya Mdzomba show with our OptoDrum that visual behavior benefits from Nogo-A neutralization after retinal damage typically found in diabetic retinopathy or glaucoma.
Expert to Expert Interview with Dr. Jeff Jamison (Experimentica Ltd)
Watch the interview with our new collaboration partner Dr. Jeff Jamison, Director of In Vivo Pharmacology at Experimentica Ltd, and developer of AcuiSee.
OptoDrum paper by Berve et al, on Neuroinflammation
In this recent paper, Berve et al show with our OptoDrum the harm of neuroinflammation on the visual system, and the benefits of proper treatments.
Webinar: Visual Acuity as a Relevant Phenotype in Mouse Models of Rare Disease
The Jackson Laboratory will introduce their Neurobehavior Phenotyping Core, in which they also do visual acuity measurements. They will present two examples where the OptoDrum has been used to characterizte vision in animal models for rare disease: The Charcot-Marie-Tooth-disease, and Multiple-Sulfatase-Deficiency.
Expert to Expert Interview with Prof. Botond Roska (IOB)
Watch Striatech’s Expert to Expert Interview with Prof. Botond Roska from the Institute of Molecular and Clinical Ophthalmology Basel (IOB).