Your Experts for Neuroscience Testing Tools

This study evaluated whether antibody-driven mouse models of neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) reproduce the distinct visual outcomes observed in patients. Researchers induced experimental autoimmune encephalomyelitis and administered disease-specific antibodies before assessing visual acuity, retinal structure, and optic nerve pathology over time. Both models developed similar visual impairment and retinal degeneration, despite subtle histological differences in optic nerve inflammation. Visual acuity was measured using the OptoDrum to monitor disease progression.

In a genome-wide association study in East Asian populations, Jiang et al investigated genetic risk factors for pathological myopia (PM), a leading cause of blindness. They identified LILRB2 as a new candidate gene associated with PM. LILRB2 upregulation promotes fatty acid synthesis and lipid accumulation, leading to choroidal dysfunction and PM development, both in human patients and in mouse models. These findings provide insights into the molecular mechanisms of PM pathogenesis related to lipid metabolism disorders. Striatech’s Photorefractor was used to measure refraction errors in mice, while the Keratometer was employed to measure corneal curvature. These tools allowed for precise ocular measurements in the animal models, contributing to the understanding of PM’s genetic and physiological aspects.

The Striatech Myopia Suite combines automated refractive state measurement and corneal curvature analysis into one seamless workflow. Developed with Prof. Frank Schaeffel, it enables precise, reliable data collection in small animal myopia research.

We’re excited to see how many research groups are presenting work at ARVO 2026 that includes Striatech technology. To help you navigate the packed program, we’ve highlighted selected talks and posters using our systems — organized by day and disease area.