Expert Talks

Striatech Online Journal Club

We host a series of online journal clubs, highlighting the use and the applications of our products. Scientists present their projects and new data, and you can learn about the latest developments in the field. We always schedule time for Q&A at the end of the presentation so that you can ask your questions and discuss the findings.

Journal Clubs and Webinars

Featured image for “Journal Club: In Vivo Modeling of Immune-mediated Optic Neuropathies”
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Wednesday, 09 Nov 2022

Journal Club: In Vivo Modeling of Immune-mediated Optic Neuropathies

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Oliver W. Gramlich, Ph.D. - The University of Iowa
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This presentation will outline the pathobiology and visual phenotype of immune mediated optic neuropathies that include Multiple Sclerosis (MS), Neuromylitis optica spectrum disorders (NMOSD), and Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).
Featured image for “Journal Club: Endothelial Caspase-9 Mediates Inflammatory and Vision Function Changes in Retinal Vascular Injury”
Q&A available
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Wednesday, 20 Jul 2022

Journal Club: Endothelial Caspase-9 Mediates Inflammatory and Vision Function Changes in Retinal Vascular Injury

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Crystal Colón Ortiz, Ph.D. - Columbia University Medical Center
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In retinal vein occlusion (RVO), non-apoptotic expression of endothelial caspase-9 (EC Casp9) induces pathology including retinal edema, capillary ischemia, and neurodegeneration. Crystal Colón Ortiz presents mechanistic insights into EC Casp9 action, and the behavioral consequences such as contrast sensitivity decline.
  • Applications:
Featured image for “Journal Club: Anti-FcRn Treatment in Antibody-Associated Experimental Autoimmune Encephalomyelitis”
Q&A available
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Tuesday, 22 Mar 2022

Journal Club: Anti-FcRn Treatment in Antibody-Associated Experimental Autoimmune Encephalomyelitis

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Jana Remlinger, MSc - Department of Neurology, Inselspital, Bern University Hospital and Department for BioMedical Research (DBMR)
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Jana Remlinger et al. showed preserved visual function and ameliorated course of disease after anti-FcRn treatment in an experimental model using a monoclonal MOG-IgG to mimic MOGAD.
Featured image for “Webinar: AcuiSee – Rodent Visual Acuity Using Behavioral Conditioning”
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Wednesday, 17 Nov 2021

Webinar: AcuiSee – Rodent Visual Acuity Using Behavioral Conditioning

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Dr. Jeffrey A Jamison - Experimentica Ltd.
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In this Webinar, Dr. Jeff Jamison will talk about “AcuiSee”, with which one can measure rodent vision based on an operant conditioning paradigm. Jeff is the developer of AcuiSee, and he now works as Director of In-Vivo Pharmacology at Experimentica.
Featured image for “Journal Club: IR Photorefraction and IR Photokeratometry – Measuring Refractive State and Corneal Curvature in Animals and Humans”
Q&A available
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Thursday, 07 Oct 2021

Journal Club: IR Photorefraction and IR Photokeratometry – Measuring Refractive State and Corneal Curvature in Animals and Humans

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Prof. Frank Schaeffel - University of Tübingen, Germany
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It is difficult to measure small eyes of animal models. In this Journal Club, Prof. Frank Schaeffel presents his inventions for IR photorefraction and IR photokeratometry that facilitate such measurements. He focuses on the history, application, advantages, optics, software algorithms and calibration.
Featured image for “Journal Club: Echolocation with Light – A New Form of Active Sensing in Fish?”
Q&A available
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Thursday, 22 Jul 2021

Journal Club: Echolocation with Light – A New Form of Active Sensing in Fish?

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Prof. Nico K. Michiels - University of Tübingen, Germany
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Some fish use active photolocation: Their eyes emit light to detect predators or pray in this spotlight. In this Journal Club, Prof. Nico Michiels from the University of Tübingen will talk about his fascinating journey in which he has discovered this phenomenon.
Featured image for “Journal Club: Assessing Neuroinflammation-related Neural Damage by Monitoring the Retinotectal System”
Q&A available
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Thursday, 27 May 2021

Journal Club: Assessing Neuroinflammation-related Neural Damage by Monitoring the Retinotectal System

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PD Dr. Janos Groh - Department of Neurology, Section of Developmental Neurobiology, University Hospital Würzburg
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Neuroinflammation amplifies neural damage caused by genetic disorders or aging. Groh et al show that neuroinflammation has deleterious consequences for the optic nerve, and disease progression can be monitored with the OptoDrum.
Featured image for “Journal Club: Restoring vision – Optogenetic gene therapy targeted at human ON-bipolar cells”
Q&A available
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Thursday, 25 Mar 2021

Journal Club: Restoring vision – Optogenetic gene therapy targeted at human ON-bipolar cells

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Dr. Elmar Hulliger - Institute of Physiology, University of Bern
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Optogenetic gene therapy holds great promise for healing blindness. Hulliger et al have developed a new promoter that effectively targets human ON bipolar cells. This is an important step towards clinical applications of optogenetic gene therapy for restoring vision.
Featured image for “Journal Club: The role of Nogo-A in visual deficits induced by retinal injury.”
Q&A available
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Thursday, 28 Jan 2021

Journal Club: The role of Nogo-A in visual deficits induced by retinal injury.

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Julius Baya Mdzomba, PhD - Université Laval
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Nogo-A, an inhibitor of neural growth, prevents regeneration after injury. Blocking of Nogo-A aides recovery, also in the visual system after retinal damage. Baya Mdzomba show with our OptoDrum that visual behavior benefits from Nogo-A neutralization after retinal damage typically found in diabetic retinopathy or glaucoma.
Featured image for “Webinar: Visual Acuity as a Relevant Phenotype in Mouse Models of Rare Disease”
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Thursday, 08 Oct 2020

Webinar: Visual Acuity as a Relevant Phenotype in Mouse Models of Rare Disease

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Zoë Bichler, PhD - The Jackson Laboratory
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Maximiliano Presa, PhD - The Jackson Laboratory
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The Jackson Laboratory will introduce their Neurobehavior Phenotyping Core, in which they also do visual acuity measurements. They will present two examples where the OptoDrum has been used to characterizte vision in animal models for rare disease: The Charcot-Marie-Tooth-disease, and Multiple-Sulfatase-Deficiency.
Featured image for “Journal Club: Measuring Visual Acuity and Contrast Sensitivity by Optomotor Reflex in Rodents”
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Thursday, 02 Apr 2020

Journal Club: Measuring Visual Acuity and Contrast Sensitivity by Optomotor Reflex in Rodents

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Dr. Thomas Münch - Striatech
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Dr. Kaushikaram Subramanian - Max Planck Institute of Molecular Cell Biology and Genetics
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Prof. Volker Enzmann - Department of Ophthalmology, University of Bern
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In vision research, observing the optomotor reflex (OMR) is an important and widely established method for assessing visual acuity and contrast sensitivity in rodents. In this event, we will hear about several applications of OMR measuremnts, ranging from quantification of retinal degeneration to characterization of night vision.