Behavioral Vision Testing Made Simple


AcuiSee automatically determines the visual abilities of mice, rats, or other laboratory animals. Based on operant conditioning, AcuiSee's fully automated and reliable analysis finds visual acuity and contrast sensitivity quickly and objectively. AcuiSee has been developed by the company of the same name, Acuisee LLC. Striatech has teamed up with Acuisee and their lead scientist, Dr. Jeff Jamison.

AcuiSee offers you a psychophysical method to explore visual behavior in a wide range of research animals. Based upon the principles of operant conditioning, you can reliably and reproducibly determine visual acuity or contrast sensitivity in a convenient, automated, fast, and objective way.


Measure visual abilities

  • Contrast sensitivity
  • Visual acuity
  • Track retinal degeneration
  • Evaluate new treatment options (stem cells, optogenetics, neuroprotection, ...)


Efficacy and safety testing

  • Efficacy: test novel ophthalmic drugs
  • Safety: screen for side effects of new compounds

Disease Models

Track disease progression

  • Retinal degeneration
  • Glaucoma
  • Axon degeneration
  • Axon regeneration
  • Multiple Sclerosis
  • Neuroinflammation
  • Stroke
  • Diabetes
  • Aging


Vision defect screening

  • Testing effects of environmental stress
  • Testing effects of neurotoxic substances

Cognitive Behavior

Decision making

  • Forced choice discrimination
  • Operant testing similar to clinical experience

AcuiSee: Briefly explained

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Background on AcuiSee

History of AcuiSee, and Differences to OptoDrum

Watch our expert interview to learn more about the background of AcuiSee: how it works, why Jeff Jamison developed it, and how AcuiSee measures vision differently than the OptoDrum.

The AcuiSee Testing Procedure: A 3-Step Process


Food Deprivation and Acclimation

Follow a few simple food deprivation guidelines before your experiments with AcuiSee. In addition, your animals should get familiarized with the chamber.  



Training consists of two 45 minute sessions per day. Animals have access to two touch panels - one in front of alternating black and white bars, the other with brightness-matched white noise. A food reward is given whenever the animal chooses the bars. Most animals reach criteria (usually: 70% correct) in 10-14 days, while a few take longer. Once trained, animals can be evaluated for visual acuity (spatial density threshold) as well as contrast sensitivity.



Testing begins with an easy target (stripe pattern) on trial 1. A correct response results in a more difficult target on the next trial until the visual threshold for the animal is determined.
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