Some fish use active photolocation: Their eyes emit light to detect predators or pray in this spotlight. In this Journal Club, Prof. Nico Michiels from the University of Tübingen will talk about his fascinating journey in which he has discovered this phenomenon.
In this video, Prof Volker Enzmann highlights an important topic: the relationship between retinal damage and optomotor behavior output is not necessarily linear, and it needs to be established for individual disease models. In the case of laser-induced local retinal damage, the optomotor behavior is only weakly affected, reflecting the surprising robustness of this reflex.
Summer Special: Schedule a free 14-day trial period and have the OptoDrum visit your lab!
Neuroinflammation amplifies neural damage caused by genetic disorders or aging. Groh et al show that neuroinflammation has deleterious consequences for the optic nerve, and disease progression can be monitored with the OptoDrum.
At this year’s ARVO, one of our OptoDrum users – Ms Anna Potenski from Columbia University – is presenting a poster on the topic of “Elucidating endothelial caspase-9 signaling pathways in retinal vein occlusion” containing OptoDrum data.
In this video of our series “OptoDrum Applications” Prof. Volker Enzmann from the University of Bern presents research with the Sodium Iodate Model (NaIO3) of Retinal Degeneration in mice.
In vision research, observing the optomotor reflex (OMR) is an important and widely established method for assessing visual acuity and contrast sensitivity in rodents. In this event, we will hear about several applications of OMR measuremnts, ranging from quantification of retinal degeneration to characterization of night vision.
Optogenetic gene therapy holds great promise for healing blindness. Hulliger et al have developed a new promoter that effectively targets human ON bipolar cells. This is an important step towards clinical applications of optogenetic gene therapy for restoring vision.
The lot has now fallen: We have a winner for our Advent calendar raffle from December 2020 where you could win one of our DarkAdapt boxes.
Nogo-A, an inhibitor of neural growth, prevents regeneration after injury. Blocking of Nogo-A aides recovery, also in the visual system after retinal damage. Baya Mdzomba show with our OptoDrum that visual behavior benefits from Nogo-A neutralization after retinal damage typically found in diabetic retinopathy or glaucoma.