AcuiSee
AcuiSee automatically determines the visual abilities of mice, rats, or other laboratory animals. Based on operant conditioning, AcuiSee's fully automated and reliable analysis finds visual acuity and contrast sensitivity quickly and objectively. AcuiSee has been developed by the company of the same name, Acuisee LLC. Striatech has teamed up with Acuisee and their lead scientist, Dr. Jeff Jamison.
AcuiSee offers you a psychophysical method to explore visual behavior in a wide range of research animals. Based upon the principles of operant conditioning, you can reliably and reproducibly determine visual acuity or contrast sensitivity in a convenient, automated, fast, and objective way.
Ophthalmology
Measure visual abilities- Contrast sensitivity
- Visual acuity
- Track retinal degeneration
- Evaluate new treatment options (stem cells, optogenetics, neuroprotection, ...)
Pharmacology
Efficacy and safety testing- Efficacy: test novel ophthalmic drugs
- Safety: screen for side effects of new compounds
Disease Models
Track disease progression- Retinal degeneration
- Glaucoma
- Axon degeneration
- Axon regeneration
- Multiple Sclerosis
- Neuroinflammation
- Stroke
- Diabetes
- Aging
Toxicology
Vision defect screening- Testing effects of environmental stress
- Testing effects of neurotoxic substances
Cognitive Behavior
Decision making- Forced choice discrimination
- Operant testing similar to clinical experience
AcuiSee: Briefly explained
Watch Video
DOwnload Brochure
Background on AcuiSee
History of AcuiSee, and Differences to OptoDrum
Watch our expert interview to learn more about the background of AcuiSee: how it works, why Jeff Jamison developed it, and how AcuiSee measures vision differently than the OptoDrum.
The AcuiSee Testing Procedure: A 3-Step Process
1
Food Deprivation and Acclimation
Follow a few simple food deprivation guidelines before your experiments with AcuiSee. In addition, your animals should get familiarized with the chamber.
2
Training
Training consists of two 45 minute sessions per day. Animals have access to two touch panels - one in front of alternating black and white bars, the other with brightness-matched white noise. A food reward is given whenever the animal chooses the bars. Most animals reach criteria (usually: 70% correct) in 10-14 days, while a few take longer. Once trained, animals can be evaluated for visual acuity (spatial density threshold) as well as contrast sensitivity.
3