Albino mice, with their characteristic white fur and red eyes due to melanin deficiency, experience impaired vision, particularly in retinal development, affecting neuron targeting from the retina to the brain. Slavi et al. identified CyclinD2 as crucial in this process, finding its downregulation disrupts the cell cycle and RGC balance. Increasing intracellular calcium levels to upregulate CyclinD2 restored proper cell cycle progression and depth perception in albino mice, suggesting potential therapies for albinism-related vision disorders.
New Sales Partner for North America
Striatech is excited to announce our partnership with Phoenix-Micron, Inc., making them our exclusive sales representative for the USA and Canada. This collaboration enhances accessibility to our expanding product portfolio, particularly benefiting the North American scientific community. We’re committed to supporting your scientific pursuits and welcome inquiries about our products and discussions on your research needs.
Journal Club: Developing a Novel Gene Therapy for Kcnv2 Retinopathy
This Journal Club demonstrates the effectiveness of an AAV-based gene therapy in rescuing vision and restoring normal retinal responses in a mouse model of KCNV2 retinopathy, a genetic form of irreversible blindness caused by mutations in the Kv8.2 subunit of voltage-gated potassium channels. Efficacy tests were carried out with Striatech’s OptoDrum and ScotopicKit, among others.
For Christmas We Give to Support Vision Researchers
This year, Striatech is once again donating to the PRO RETINA Foundation to support their great work for retinal researchers and affected individuals.
SfN Neuroscience 2023 in Washington, D.C. | November 11-15
Meet Striatech at the 2023 SfN Neuroscience meeting in Washington, D.C., November 11-15. Stop by our booth #1339 and see our OptoDrum, Photorefractor and Keratometer devices in action!
Neuroprotective Properties of Vitamin C Show Supporting Effects in Treating Glaucoma Patients
In their recent paper, Song Li and Tatjana C. Jakobs (Harvard Schepens Eye Research Institute) show how they have identified Vitamin C as a potential neuroprotective substance that could be used clinically in patients suffering from glaucoma. Striatech’s OptoDrum was used as readout tool for visual performance.
Journal Club: Monitoring Refractive Development in Mice to Investigate Mechanisms of Myopia
This Journal Club will demonstrate the usefulness and feasibility of refractive error measurements in mice, and it will discuss how measurements with Striatech’s automated Photorefractor can elucidate mechanisms of refractive development.
Euretina Congress in Amsterdam | October 5-8
Meet us at the 2023 Euretina Congress in Amsterdam and see our OptoDrum, Photorefractor and Keratometer in action! October 5 – 8
Symposium: Opportunities, Hopes, and Challenges in Translating Visual Restoration from Mouse to Human
Striatech celebrates its 5th anniversary with a top-class Symposium on the topic of translating visual restoration from mouse to human. Presentations will be given by Professor Eberhart Zrenner (University of Tübingen), Professor Constance Cepko (Harvard Medical School) and Miikka Terho (Pioneer Retina Implant Patient, Finland). In addition, the speakers will highlight important aspects and directions in this area of research in a moderated panel discussion.
Journal Club: Postsynaptic Neuronal Activity Promotes Retinal Axon Regeneration
This Journal Club provides insights into mechanisms that promote retinal ganglion cell (RGC) axon regeneration in vertebrates after optic nerve injury.