ARVO Meeting 2024 in Seattle | May 5-9
Join us at the 2024 ARVO Meeting in Seattle, WA from May 5 to 9! Come experience our state-of-the-art OptoDrum, Photorefractor, and Keratometer firsthand. Don’t miss this opportunity to explore our innovative vision research tools in action and join one of our special events. See you there!
Unveiling the Mysteries of Albinism: Disrupted Retinal Harmony Due to CyclinD2 Deficiency
Albino mice, with their characteristic white fur and red eyes due to melanin deficiency, experience impaired vision, particularly in retinal development, affecting neuron targeting from the retina to the brain. Slavi et al. identified CyclinD2 as crucial in this process, finding its downregulation disrupts the cell cycle and RGC balance. Increasing intracellular calcium levels to upregulate CyclinD2 restored proper cell cycle progression and depth perception in albino mice, suggesting potential therapies for albinism-related vision disorders.
Journal Club: Developing a Novel Gene Therapy for Kcnv2 Retinopathy
This Journal Club demonstrates the effectiveness of an AAV-based gene therapy in rescuing vision and restoring normal retinal responses in a mouse model of KCNV2 retinopathy, a genetic form of irreversible blindness caused by mutations in the Kv8.2 subunit of voltage-gated potassium channels. Efficacy tests were carried out with Striatech’s OptoDrum and ScotopicKit, among others.
SfN Neuroscience 2023 in Washington, D.C. | November 11-15
Meet Striatech at the 2023 SfN Neuroscience meeting in Washington, D.C., November 11-15. Stop by our booth #1339 and see our OptoDrum, Photorefractor and Keratometer devices in action!
Neuroprotective Properties of Vitamin C Show Supporting Effects in Treating Glaucoma Patients
In their recent paper, Song Li and Tatjana C. Jakobs (Harvard Schepens Eye Research Institute) show how they have identified Vitamin C as a potential neuroprotective substance that could be used clinically in patients suffering from glaucoma. Striatech’s OptoDrum was used as readout tool for visual performance.