Albino mice, with their characteristic white fur and red eyes due to melanin deficiency, experience impaired vision, particularly in retinal development, affecting neuron targeting from the retina to the brain. Slavi et al. identified CyclinD2 as crucial in this process, finding its downregulation disrupts the cell cycle and RGC balance. Increasing intracellular calcium levels to upregulate CyclinD2 restored proper cell cycle progression and depth perception in albino mice, suggesting potential therapies for albinism-related vision disorders.
Neuroprotective Properties of Vitamin C Show Supporting Effects in Treating Glaucoma Patients
In their recent paper, Song Li and Tatjana C. Jakobs (Harvard Schepens Eye Research Institute) show how they have identified Vitamin C as a potential neuroprotective substance that could be used clinically in patients suffering from glaucoma. Striatech’s OptoDrum was used as readout tool for visual performance.
OptoDrum Applications – Multiple Sulfatase Deficiency (MSD)
In this “OptoDrum Applications” video, Dr. Maximiliano Presa from The Jackson Laboratory presents results of his research in a model of Multiple Sulfatase Deficiency (MSD).
Can aging be reversed?
Scientists from Harvard Medical School were able to reverse the consequences of aging in the visual system, successfully treating optic nerve injury and glaucoma. Here is an overview of their 2020 study and it´s key findings.
OptoDrum paper: Role of histamine in EAE
In this recent paper, Françoise Morin et al. show with our OptoDrum that a lack of histamine, unexpectedly, has no impact on the development and severity of Experimental Autoimmune Encephalomyelitis (EAE).
Advent Calendar Raffle 2020: We Have a Winner for our DarkAdapt Box!
The lot has now fallen: We have a winner for our Advent calendar raffle from December 2020 where you could win one of our DarkAdapt boxes.
Expert to Expert Interview with Dr. Jeff Jamison (Experimentica Ltd)
Watch the interview with our new collaboration partner Dr. Jeff Jamison, Director of In Vivo Pharmacology at Experimentica Ltd, and developer of AcuiSee.
OptoDrum paper by Berve et al, on Neuroinflammation
In this recent paper, Berve et al show with our OptoDrum the harm of neuroinflammation on the visual system, and the benefits of proper treatments.
Expert to Expert Interview with Prof. Botond Roska (IOB)
Watch Striatech’s Expert to Expert Interview with Prof. Botond Roska from the Institute of Molecular and Clinical Ophthalmology Basel (IOB).
Now available on demand: Journal Club with Jackson Laboratory
You couldn‘t attend our Journal Club on Oct 8th? Watch it now on demand!Register below to watch the presentation by …