In this recent paper, Françoise Morin et al. show with our OptoDrum that a lack of histamine, unexpectedly, has no impact on the development and severity of Experimental Autoimmune Encephalomyelitis (EAE).
Uveitis – chances for new treatments
The “Standardization of Uveitis Nomenclature (SUN) Working Group” published classification criteria to help with better disease-specific approaches to diagnosis and treatment. For animal models of Uveitis, our OptoDrum provides a convenient readout tool to characterize diesease progression.
OptoDrum Applications – Induced Experimental Autoimmune Encephalomyelitis (EAE)
In this video of our series “OptoDrum Applications” Prof. Volker Enzmann from the University of Bern presents the results of his research on induced EAE, a model for optic neuropathy and multiple sclerosis.
Journal Club: Echolocation with Light – A New Form of Active Sensing in Fish?
Some fish use active photolocation: Their eyes emit light to detect predators or pray in this spotlight. In this Journal Club, Prof. Nico Michiels from the University of Tübingen will talk about his fascinating journey in which he has discovered this phenomenon.
OptoDrum Applications: Limitations of Optomotor Measurements for Laser-induced Damage
In this video, Prof Volker Enzmann highlights an important topic: the relationship between retinal damage and optomotor behavior output is not necessarily linear, and it needs to be established for individual disease models. In the case of laser-induced local retinal damage, the optomotor behavior is only weakly affected, reflecting the surprising robustness of this reflex.
Summer Special: OptoDrum free 14-day trial period
Summer Special: Schedule a free 14-day trial period and have the OptoDrum visit your lab!
Journal Club: Assessing Neuroinflammation-related Neural Damage by Monitoring the Retinotectal System
Neuroinflammation amplifies neural damage caused by genetic disorders or aging. Groh et al show that neuroinflammation has deleterious consequences for the optic nerve, and disease progression can be monitored with the OptoDrum.
ARVO 2021: Poster with OptoDrum Data by Columbia University
At this year’s ARVO, one of our OptoDrum users – Ms Anna Potenski from Columbia University – is presenting a poster on the topic of “Elucidating endothelial caspase-9 signaling pathways in retinal vein occlusion” containing OptoDrum data.
OptoDrum Applications – Sodium Iodate Model of Retinal Degeneration
In this video of our series “OptoDrum Applications” Prof. Volker Enzmann from the University of Bern presents research with the Sodium Iodate Model (NaIO3) of Retinal Degeneration in mice.
Journal Club: Measuring Visual Acuity and Contrast Sensitivity by Optomotor Reflex in Rodents
In vision research, observing the optomotor reflex (OMR) is an important and widely established method for assessing visual acuity and contrast sensitivity in rodents. In this event, we will hear about several applications of OMR measuremnts, ranging from quantification of retinal degeneration to characterization of night vision.